Pharmacology and the Nursing Process by Linda Lane Lilley: Practice Exam

How do ARBs differ from ACE inhibitors in their action?

1. ARBs block vasoconstriction and secretion of aldosterone

2. ARBs increase the breakdown of bradykinins

3. ARBs promote the secretion of aldosterone

4. ARBs increase SVR

The correct answer is: ARBs block vasoconstriction and secretion of aldosterone

ARBs, or angiotensin receptor blockers, work by blocking the action of angiotensin II, a hormone that constricts blood vessels and stimulates the secretion of aldosterone. This results in vasodilation and decreased levels of aldosterone, leading to lower blood pressure. This is different from ACE inhibitors, which work by inhibiting the production of angiotensin II. Option B is incorrect because ARBs do not affect the breakdown of bradykinins. Option C is incorrect because ARBs do not promote the secretion of aldosterone. Option D is incorrect because ARBs do not increase systemic vascular resistance (SVR), rather they decrease it.