Pharmacology and the Nursing Process by Linda Lane Lilley: Practice Exam

Montelukast has fewer drug interactions than which two drugs?

1. Zafirlukast and zileuton

2. Phenobarbital and rifampin

3. Ibuprofen and acetaminophen

4. Aspirin and codeine

The correct answer is: Zafirlukast and zileuton

Montelukast has fewer drug interactions when compared to Zafirlukast and zileuton because both Zafirlukast and zileuton are known to interact with multiple drugs and substances. Zafirlukast has been shown to interact with anti-fungal medications, certain antibiotics, and the blood thinner warfarin. Zileuton can interact with drugs that affect liver enzymes, such as seizure medications like phenobarbital and antibiotics like rifampin. In contrast, Montelukast has been shown to have fewer interactions with other drugs and substances, making it a safer option for individuals who may be taking multiple medications for their health. The other options, ibuprofen and acetaminophen, aspirin and codeine, and phenobarbital and rifampin, are not mentioned in relation to Montelukast and therefore are not