Pharmacology and the Nursing Process by Linda Lane Lilley: Practice Exam

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What adverse effect is less likely to occur with ARBs compared to ACE inhibitors?

  1. Fatigue

  2. Diarrhea

  3. Cough

  4. Hyperkalemia

The correct answer is: Cough

When taking ACE inhibitors, one common side effect is a persistent cough that can be bothersome for some individuals. This is because ACE inhibitors increase levels of bradykinin, a substance that can cause constriction and irritation in the airways. However, this adverse effect is less likely to occur with ARBs because they do not have an impact on bradykinin levels. Fatigue and hyperkalemia can occur with both ARBs and ACE inhibitors, so they are not the correct answer. Diarrhea is not a known adverse effect of either medication type, so it is also an incorrect option. While all medications have the potential to cause adverse effects, ARBs are generally well-tolerated and do not cause as many unwanted symptoms as ACE inhibitors.