Pharmacology and the Nursing Process by Linda Lane Lilley: Practice Exam

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What is Captopril (Capoten) notable for in the class of ACE inhibitors?

  1. It is the longest-acting ACE inhibitor

  2. It is the most potent ACE inhibitor

  3. It is considered the first and prototypical ACE inhibitor

  4. It is the only ACE inhibitor not requiring liver function for activation

The correct answer is: It is considered the first and prototypical ACE inhibitor

Captopril (Capoten) is notable for its role as the first and prototypical ACE inhibitor. While A and B may seem like plausible options, there is no evidence to suggest that Captopril is the longest-acting or most potent ACE inhibitor. In fact, there are other ACE inhibitors, such as Enalapril and Lisinopril, that have longer half-lives and are more potent than Captopril. Additionally, the fact that Captopril is the only ACE inhibitor that does not require liver function for activation is not accurate. There are other ACE inhibitors, such as Ramipril and Quinapril, that do not require liver function for activation. Therefore, the correct answer is C.