Pharmacology and the Nursing Process by Linda Lane Lilley: Practice Exam

What is the action mechanism of Fondaparinux?

1. Selective inhibition of factor Xa

2. Direct thrombin inhibition

3. Vitamin K antagonist

4. Platelet aggregation inhibitor

The correct answer is: Selective inhibition of factor Xa

Fondaparinux is a synthetic anticoagulant that works by selectively inhibiting the activation of factor Xa, an enzyme involved in the blood coagulation cascade. This prevents the formation of blood clots. Option B, direct thrombin inhibition, refers to a different type of anticoagulant medication that directly blocks the activity of thrombin, a protein involved in the blood coagulation process. Option C, vitamin K antagonist, refers to a class of blood thinners that inhibit the production of vitamin K-dependent clotting factors. And option D, platelet aggregation inhibitor, refers to medications that prevent platelets from clumping together, thereby reducing the risk of blood clot formation. None of these options are the correct action mechanism for Fondaparinux, making option A the correct answer.