Pharmacology and the Nursing Process by Linda Lane Lilley: Practice Exam

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Why is continuous monitoring of lab values like INR and aPTT essential with thrombolytic drugs?

  1. To adjust the dose daily

  2. To monitor for therapeutic effects

  3. To check for the occurrence of fibrinolysis

  4. To decide when to stop therapy

The correct answer is: To check for the occurrence of fibrinolysis

Continuous monitoring of lab values like INR and aPTT is essential with thrombolytic drugs to check for the occurrence of fibrinolysis. Thrombolytic drugs work by breaking down blood clots,which is a potential risk for bleeding. INR and aPTT tests measure how quickly your blood clots, and can help healthcare providers determine if the thrombolytic drug is working as intended and not causing too much bleeding. Option A is incorrect because the dose of thrombolytic drugs is typically given as a one-time administration. Option B is not the primary reason for monitoring these lab values, although it may be considered. Option D is incorrect because the decision to stop therapy would be based on the patient's overall response to treatment, not solely on lab values.